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Progress in structural studies of telomerase

Telomerase is the ribonucleoprotein (RNP) reverse transcriptase responsible for synthesizing the 3′ ends of linear chromosomes. It plays critical roles in tumorigenesis, cellular aging, and stem cell renewal. The past two years have seen exciting progress in determining telomerase holoenzyme archite...

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Bibliografiska uppgifter
Huvudupphovsmän: Miracco, Edward J., Jiang, Jiansen, Cash, Darian, Feigon, Juli
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984607/
https://ncbi.nlm.nih.gov/pubmed/24508601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.01.008
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