Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans

AIMS: Studies have shown association between common variants in the α6–β3 nicotinic receptor subunit gene cluster and nicotine dependence in European Ancestry populations. We investigate whether this generalizes to African Americans, whether the association is specific to nicotine dependence, and wh...

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Hauptverfasser: Culverhouse, Robert C., Johnson, Eric O., Breslau, Naomi, Hatsukami, Dorothy K., Sadler, Brooke, Brooks, Andrew I., Hesselbrock, Victor M., Schuckit, Marc A., Tischfield, Jay A., Goate, Alison M., Saccone, Nancy L., Bierut, Laura J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984604/
https://ncbi.nlm.nih.gov/pubmed/24401102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/add.12478
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