Autophagy Induced by Tumor Necrosis Factor α Mediates Intrinsic Apoptosis in Trophoblastic Cells

To investigate the interconnection of apoptosis and autophagy in trophoblastic cells, we treated JEG-3 cells with tumor necrosis factor α (TNF-α) after transfecting LC3 or Beclin 1 or calpain small interfering RNA (siRNA), which blocks cleavage of autophagy-related gene 5 (Atg5) into N-terminal trun...

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Bibliografske podrobnosti
Main Authors: Cha, Hyun-Hwa, Hwang, Jae Ryoung, Kim, Hyo-Youn, Choi, Suk-Joo, Oh, Soo-young, Roh, Cheong-Rae
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2014
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984484/
https://ncbi.nlm.nih.gov/pubmed/24198074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113508816
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