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Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating FAO defects in vivo in humans has entailed complex and invasive methodologies. Recently, the identification of genetic blocks in FAO has been v...

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Detalhes bibliográficos
Main Authors: Mihalik, Stephanie J., Goodpaster, Bret H., Kelley, David E., Chace, Donald H., Vockley, Jerry, Toledo, Frederico G.S., DeLany, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984458/
https://ncbi.nlm.nih.gov/pubmed/20111019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.510
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