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Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity

Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating FAO defects in vivo in humans has entailed complex and invasive methodologies. Recently, the identification of genetic blocks in FAO has been v...

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Библиографические подробности
Главные авторы: Mihalik, Stephanie J., Goodpaster, Bret H., Kelley, David E., Chace, Donald H., Vockley, Jerry, Toledo, Frederico G.S., DeLany, James P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984458/
https://ncbi.nlm.nih.gov/pubmed/20111019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.510
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