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Preclinical characterization of an anti-methamphetamine monoclonal antibody for human use

Ch-mAb7F9, a human-mouse chimeric monoclonal antibody (mAb) designed to bind (+)-methamphetamine (METH) with high affinity and specificity, was produced as a treatment medication for METH abuse. In these studies, we present the preclinical characterization that provided predictive evidence that ch-m...

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Autors principals: Stevens, Misty W, Tawney, Rachel L, West, C Michael, Kight, Alicia D, Henry, Ralph L, Owens, S Michael, Gentry, W Brooks
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984342/
https://ncbi.nlm.nih.gov/pubmed/24492290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27620
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