Generation of human single-chain variable fragment antibodies specific to dengue virus non-structural protein 1 that interfere with the virus infectious cycle

Severe forms of dengue virus (DENV) infection frequently cause high case fatality rate. Currently, there is no effective vaccine against the infection. Clinical cases are given only palliative treatment as specific anti-DENV immunotherapy is not available and it is urgently required. In this study,...

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Main Authors: Poungpair, Ornnuthchar, Bangphoomi, Kunan, Chaowalit, Prapaipit, Sawasdee, Nunghathai, Saokaew, Nichapatr, Choowongkomon, Kiattawee, Chaicumpa, Wanpen, Yenchitsomanus, Pa-thai
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984335/
https://ncbi.nlm.nih.gov/pubmed/24492300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27874
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