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The MAPK-activated protein kinase 2 mediates gemcitabine sensitivity in pancreatic cancer cells

Pancreatic carcinoma is the major clinical entity where the nucleoside analog gemcitabine is used for first-line therapy. Overcoming cellular resistance toward gemcitabine remains a major challenge in this context. This raises the need to identify factors that determine gemcitabine sensitivity in pa...

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Detalles Bibliográficos
Main Authors: Köpper, Frederik, Binkowski, Anna Maria, Bierwirth, Cathrin, Dobbelstein, Matthias
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984311/
https://ncbi.nlm.nih.gov/pubmed/24556918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28292
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