The NAD(+) synthesizing enzyme nicotinamide mononucleotide adenylyltransferase 2 (NMNAT-2) is a p53 downstream target

NAD(+) metabolism plays key roles not only in energy production but also in diverse cellular physiology. Aberrant NAD(+) metabolism is considered a hallmark of cancer. Recently, the tumor suppressor p53, a major player in cancer signaling pathways, has been implicated as an important regulator of ce...

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Autori principali: Pan, Lu-Zhe, Ahn, Dae-Gyun, Sharif, Tanveer, Clements, Derek, Gujar, Shashi A, Lee, Patrick WK
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984302/
https://ncbi.nlm.nih.gov/pubmed/24552824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28128
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