The NAD(+) Synthesis Enzyme Nicotinamide Mononucleotide Adenylyltransferase (NMNAT1) Regulates Ribosomal RNA Transcription

The chromosomal region encoding the nuclear NAD(+) synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequently deleted in human cancer. We describe evidence that NMNAT1 interacts with the nucleolar repressor protein nucleomethylin and is involved in regulating rRNA transc...

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Detalhes bibliográficos
Main Authors: Song, Tanjing, Yang, Leixiang, Kabra, Neha, Chen, Lihong, Koomen, John, Haura, Eric B., Chen, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774361/
https://ncbi.nlm.nih.gov/pubmed/23737528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470302
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