The NAD(+) Synthesis Enzyme Nicotinamide Mononucleotide Adenylyltransferase (NMNAT1) Regulates Ribosomal RNA Transcription

The chromosomal region encoding the nuclear NAD(+) synthesis enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT1) is frequently deleted in human cancer. We describe evidence that NMNAT1 interacts with the nucleolar repressor protein nucleomethylin and is involved in regulating rRNA transc...

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Main Authors: Song, Tanjing, Yang, Leixiang, Kabra, Neha, Chen, Lihong, Koomen, John, Haura, Eric B., Chen, Jiandong
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2013
主題:
Gene Regulation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774361/
https://ncbi.nlm.nih.gov/pubmed/23737528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.470302
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