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Germline Variation in Colorectal Risk Loci Does Not Influence Treatment Effect or Survival in Metastatic Colorectal Cancer
BACKGROUND: Colorectal cancer (CRC) risk is partly conferred by common, low-penetrance single nucleotide polymorphisms (SNPs). We hypothesized that these SNPs are associated with outcomes in metastatic CRC. METHODS: Six candidate SNPs from 8q24, 10p14, 15q13, 18q21 were investigated for their associ...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984266/ https://ncbi.nlm.nih.gov/pubmed/24727911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094727 |
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