Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production

How ω-3 and ω-6 polyunsaturated fatty acids (PUFAs) lower plasma lipid levels is incompletely understood. We previously showed that marine ω-3 PUFAs (docosahexaenoic acid [DHA] and eicosapentaenoic acid) stimulate a novel pathway, post-ER presecretory proteolysis (PERPP), that degrades apolipoprotei...

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Auteurs principaux: Pan, Meihui, Cederbaum, Arthur I., Zhang, Yuan-Li, Ginsberg, Henry N., Williams, Kevin Jon, Fisher, Edward A.
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2004
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC398425/
https://ncbi.nlm.nih.gov/pubmed/15124019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200419197
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