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Role of superoxide radical anion in the mechanism of apoB100 degradation induced by DHA in hepatic cells

VLDL is produced by the liver. Its major protein is apoB100. Docosahexaenoic acid (DHA), a dietary polyunsaturated fatty acid (PUFA), reduces VLDL levels and is used therapeutically for hypertriglyceridemia. In model systems, DHA lowers VLDL secretion by inducing presecretory apoB100 degradation, a...

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Autors principals: Andreo, Ursula, Elkind, Josh, Blachford, Courtney, Cederbaum, Arthur I., Fisher, Edward A.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177569/
https://ncbi.nlm.nih.gov/pubmed/21757500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-182725
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