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Single Nucleotide Polymorphism (SNP)-Strings: An Alternative Method for Assessing Genetic Associations

BACKGROUND: Genome-wide association studies (GWAS) identify disease-associations for single-nucleotide-polymorphisms (SNPs) from scattered genomic-locations. However, SNPs frequently reside on several different SNP-haplotypes, only some of which may be disease-associated. This circumstance lowers th...

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Detalhes bibliográficos
Main Authors: Goodin, Douglas S., Khankhanian, Pouya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984082/
https://ncbi.nlm.nih.gov/pubmed/24727690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090034
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