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Single Nucleotide Polymorphism (SNP)-Strings: An Alternative Method for Assessing Genetic Associations

BACKGROUND: Genome-wide association studies (GWAS) identify disease-associations for single-nucleotide-polymorphisms (SNPs) from scattered genomic-locations. However, SNPs frequently reside on several different SNP-haplotypes, only some of which may be disease-associated. This circumstance lowers th...

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Hlavní autoři: Goodin, Douglas S., Khankhanian, Pouya
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984082/
https://ncbi.nlm.nih.gov/pubmed/24727690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090034
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