VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion.

VAMP proteins are important components of the machinery controlling docking and/or fusion of secretory vesicles with their target membrane. We investigated the expression of VAMP proteins in pancreatic beta-cells and their implication in the exocytosis of insulin. cDNA cloning revealed that VAMP-2 a...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Regazzi, R, Wollheim, C B, Lang, J, Theler, J M, Rossetto, O, Montecucco, C, Sadoul, K, Weller, U, Palmer, M, Thorens, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7796801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07273.x
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