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The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1

RNA polymerase II (PolII) transcribes RNA within a chromatin context, with nucleosomes acting as barriers to transcription. Despite these barriers, transcription through chromatin in vivo is highly efficient, suggesting the existence of factors that overcome this obstacle. To increase the resolution...

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Bibliografske podrobnosti
Main Authors: Skene, Peter J, Hernandez, Aaron E, Groudine, Mark, Henikoff, Steven
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983905/
https://ncbi.nlm.nih.gov/pubmed/24737864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02042
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