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A comparison study of optimal and suboptimal intervention policies for gene regulatory networks in the presence of uncertainty

Perfect knowledge of the underlying state transition probabilities is necessary for designing an optimal intervention strategy for a given Markovian genetic regulatory network. However, in many practical situations, the complex nature of the network and/or identification costs limit the availability...

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Detalhes bibliográficos
Main Authors: Yousefi, Mohammadmahdi R, Dougherty, Edward R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983901/
https://ncbi.nlm.nih.gov/pubmed/24708650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1687-4153-2014-6
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