Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare and devastating disease, resulting from progressive obliteration of small caliber pulmonary arteries by proliferating vascular cells, and leading to cardiac failure, with an untreated mean survival of less than three years (1,2). PAH can complicate oth...

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Päätekijät: Germain, Marine, Eyries, Mélanie, Montani, David, Poirier, Odette, Girerd, Barbara, Dorfmüller, Peter, Coulet, Florence, Nadaud, Sophie, Maugenre, Svetlana, Guignabert, Christophe, Carpentier, Wassila, Vonk-Noordegraaf, Anton, Levy, Marilyne, Chaouat, Ari, Lambert, Jean-Charles, Marion, Bertrand M, Dupuy, Anne-Marie, Letenneur, Luc, Lathrop, Mark, Amouyel, Philippe, de Ravel, Thomy JL, Delcroix, Marion, Austin, Eric D., Robbins, Ivan M., Hemnes, Anna R., Loyd, James E., Berman-Rosenzwieg, Erika, Barst, Robyn J., Chung, Wendy K., Simonneau, Gerald, Trégouët, David A., Humbert, Marc, Soubrier, Florent
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983781/
https://ncbi.nlm.nih.gov/pubmed/23502781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2581
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