Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a rare and devastating disease, resulting from progressive obliteration of small caliber pulmonary arteries by proliferating vascular cells, and leading to cardiac failure, with an untreated mean survival of less than three years (1,2). PAH can complicate oth...

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Hlavní autoři: Germain, Marine, Eyries, Mélanie, Montani, David, Poirier, Odette, Girerd, Barbara, Dorfmüller, Peter, Coulet, Florence, Nadaud, Sophie, Maugenre, Svetlana, Guignabert, Christophe, Carpentier, Wassila, Vonk-Noordegraaf, Anton, Levy, Marilyne, Chaouat, Ari, Lambert, Jean-Charles, Marion, Bertrand M, Dupuy, Anne-Marie, Letenneur, Luc, Lathrop, Mark, Amouyel, Philippe, de Ravel, Thomy JL, Delcroix, Marion, Austin, Eric D., Robbins, Ivan M., Hemnes, Anna R., Loyd, James E., Berman-Rosenzwieg, Erika, Barst, Robyn J., Chung, Wendy K., Simonneau, Gerald, Trégouët, David A., Humbert, Marc, Soubrier, Florent
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983781/
https://ncbi.nlm.nih.gov/pubmed/23502781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2581
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