Noncanonical NF-κB Pathway Controls the Production of Type I Interferons in Antiviral Innate Immunity

Production of type I interferons (IFN-I) is a crucial innate immune mechanism against viral infections. IFN-I induction is subject to negative regulation by both viral and cellular factors, but the underlying mechanism remains unclear. We report that the noncanonical NF-κB pathway was stimulated alo...

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Huvudupphovsmän: Jin, Jin, Hu, Hongbo, Li, Haiyan S., Yu, Jiayi, Xiao, Yichuan, Brittain, George C., Zou, Qiang, Cheng, Xuhong, Mallette, Frédérick A., Watowich, Stephanie S., Sun, Shao-Cong
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983709/
https://ncbi.nlm.nih.gov/pubmed/24656046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.02.006
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