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Sequence signatures extracted from proximal promoters can be used to predict distal enhancers

BACKGROUND: Gene expression is controlled by proximal promoters and distal regulatory elements such as enhancers. While the activity of some promoters can be invariant across tissues, enhancers tend to be highly tissue-specific. RESULTS: We compiled sets of tissue-specific promoters based on gene ex...

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מידע ביבליוגרפי
Main Authors: Taher, Leila, Smith, Robin P, Kim, Mee J, Ahituv, Nadav, Ovcharenko, Ivan
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983659/
https://ncbi.nlm.nih.gov/pubmed/24156763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-10-r117
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