Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells

Many patients with acute myeloid leukemia (AML) are incurable with chemotherapy and may benefit from novel approaches. One such approach involves the transfer of T cells engineered to express chimeric antigen receptors (CARs) for a specific cell-surface antigen. This strategy depends upon preferenti...

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Main Authors: Gill, Saar, Tasian, Sarah K., Ruella, Marco, Shestova, Olga, Li, Yong, Porter, David L., Carroll, Martin, Danet-Desnoyers, Gwenn, Scholler, John, Grupp, Stephan A., June, Carl H., Kalos, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Gene Therapy
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983612/
https://ncbi.nlm.nih.gov/pubmed/24596416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-09-529537
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