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Behavioral decline and premature lethality upon pan-neuronal ferritin overexpression in Drosophila infected with a virulent form of Wolbachia

Iron is required for organismal growth. Therefore, limiting iron availability may be a key part of the host’s innate immune response to various pathogens, for example, in Drosophila infected with Zygomycetes. One way the host can transiently reduce iron bioavailability is by ferritin overexpression....

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Main Authors: Kosmidis, Stylianos, Missirlis, Fanis, Botella, Jose A., Schneuwly, Stephan, Rouault, Tracey A., Skoulakis, Efthimios M. C.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983519/
https://ncbi.nlm.nih.gov/pubmed/24772084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00066
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