Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis

Despite the prominence of iron–sulfur cluster (ISC) proteins in bioenergetics, intermediary metabolism, and redox regulation of cellular, mitochondrial, and nuclear processes, these proteins have been given scarce attention in Drosophila. Moreover, biosynthesis and delivery of ISCs to target protein...

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Bibliographic Details
Main Authors: Uhrigshardt, Helge, Rouault, Tracey A., Missirlis, Fanis
Format: Artigo
Language:Inglês
Published: Springer-Verlag 2013
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612401/
https://ncbi.nlm.nih.gov/pubmed/23444034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-0988-2
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