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Insertion mutants in Drosophila melanogaster Hsc20 halt larval growth and lead to reduced iron–sulfur cluster enzyme activities and impaired iron homeostasis

Despite the prominence of iron–sulfur cluster (ISC) proteins in bioenergetics, intermediary metabolism, and redox regulation of cellular, mitochondrial, and nuclear processes, these proteins have been given scarce attention in Drosophila. Moreover, biosynthesis and delivery of ISCs to target protein...

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Detalhes bibliográficos
Main Authors: Uhrigshardt, Helge, Rouault, Tracey A., Missirlis, Fanis
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612401/
https://ncbi.nlm.nih.gov/pubmed/23444034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-013-0988-2
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