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Least activation path for protein folding: investigation of staphylococcal nuclease folding by stopped-flow circular dichroism.

Is the pathway of protein folding determined by the relative stability of folding intermediates, or by the relative height of the activation barriers leading to these intermediates? This is a fundamental question for resolving the Levinthal paradox, which stated that protein folding by a random sear...

詳細記述

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書誌詳細
主要な著者: Su, Z D, Arooz, M T, Chen, H M, Gross, C J, Tsong, T Y
フォーマット: Artigo
言語:Inglês
出版事項: 1996
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC39833/
https://ncbi.nlm.nih.gov/pubmed/8637910
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