GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.

The TGF-beta type II receptor (T beta R-II) is a transmembrane serine/threonine kinase that, upon ligand binding, recruits and phosphorylates a second transmembrane kinase, T beta R-I, as a requirement for signal transduction. T beta R-I is phosphorylated by T beta R-II in the GS domain, a 30 amino...

ver descrição completa

Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Wieser, R, Wrana, J L, Massagué, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7774578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07214.x
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!