Mycobacterium tuberculosis Rv3402c Enhances Mycobacterial Survival within Macrophages and Modulates the Host Pro-Inflammatory Cytokines Production via NF-Kappa B/ERK/p38 Signaling

Intracellular survival plays a central role in the pathogenesis of Mycobacterium tuberculosis, a process which depends on an array of virulence factors to colonize and replicate within the host. The M. tuberculosis iron regulated open reading frame (ORF) rv3402c, encoding a conserved hypothetical pr...

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Bibliographische Detailangaben
Hauptverfasser: Li, Wu, Zhao, Quanju, Deng, Wanyan, Chen, Tian, Liu, Minqiang, Xie, Jianping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983203/
https://ncbi.nlm.nih.gov/pubmed/24722253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094418
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