Clickable, Hydrophilic Ligand for fac-[M(I)(CO)(3)](+) (M = Re/(99m)Tc) Applied in an S-Functionalized α-MSH Peptide

[Image: see text] The copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) click reaction was used to incorporate alkyne-functionalized dipicolylamine (DPA) ligands (1 and 3) for fac-[M(I)(CO)(3)](+) (M = Re/(99m)Tc) complexation into an α-melanocyte stimulating hormone (α-MSH) peptide analogue. A...

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Huvudupphovsmän: Kasten, Benjamin B., Ma, Xiaowei, Liu, Hongguang, Hayes, Thomas R., Barnes, Charles L., Qi, Shibo, Cheng, Kai, Bottorff, Shalina C., Slocumb, Winston S., Wang, Jing, Cheng, Zhen, Benny, Paul D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983144/
https://ncbi.nlm.nih.gov/pubmed/24568284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc5000115
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