A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

We identified three proteins in neutrophil cytosol of molecular size 65, 62 and 68 kDa which interact in a GTP-dependent manner with rac1 and CDC42Hs, but not with rho. Purification of p65 and subsequent peptide sequencing revealed identity to rat brain PAK65 and to yeast STE20 kinase domains. Based...

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Publicat a:EMBO J
Autors principals: Martin, G A, Bollag, G, McCormick, F, Abo, A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7744004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07189.x
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