A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

We identified three proteins in neutrophil cytosol of molecular size 65, 62 and 68 kDa which interact in a GTP-dependent manner with rac1 and CDC42Hs, but not with rho. Purification of p65 and subsequent peptide sequencing revealed identity to rat brain PAK65 and to yeast STE20 kinase domains. Based...

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Библиографические подробности

Опубликовано в::	EMBO J
Главные авторы:	Martin, G A, Bollag, G, McCormick, F, Abo, A
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 1995
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7744004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07189.x
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