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Inhibition of Epithelial-to-Mesenchymal Transition (EMT) in Cancer by Nitric Oxide: Pivotal Roles of Nitrosylation of NF-κB, YY1 and Snail

Treatment of cancer cell lines with high levels of nitric oxide (NO) via NO donors, such as DETANONOate, inhibits cell growth and survival pathways and sensitizes resistant tumor cells to apoptosis by chemoimmunotherapeutic drugs. In addition, we recently have reported that NO also inhibits the epit...

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Main Authors: Bonavida, Benjamin, Baritaki, Stavroula
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982871/
https://ncbi.nlm.nih.gov/pubmed/24729932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1615/ForumImmunDisTher.2012006065
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