Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia

Lysins are bacteriophage-derived enzymes that degrade bacterial peptidoglycans. Lysin CF-301 is being developed to treat Staphylococcus aureus because of its potent, specific, and rapid bacteriolytic effects. It also demonstrates activity on drug-resistant strains, has a low resistance profile, erad...

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Detalhes bibliográficos
Main Authors: Schuch, Raymond, Lee, Han M., Schneider, Brent C., Sauve, Karen L., Law, Christina, Khan, Babar K., Rotolo, Jimmy A., Horiuchi, Yuki, Couto, Daniel E., Raz, Assaf, Fischetti, Vincent A., Huang, David B., Nowinski, Robert C., Wittekind, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982849/
https://ncbi.nlm.nih.gov/pubmed/24286983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit637
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