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The AKTion in non-canonical insulin signaling

The kinase AKT has been regarded as an obligate intermediate in the insulin signaling pathway that suppresses glucose production by inhibiting the transcription factor forkhead box O1 (FoxO1) after meals. A new study shows that, without AKT-FoxO1 signaling, insulin still contributes to postprandial...

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Détails bibliographiques
Auteurs principaux: Cheng, Zhiyong, White, Morris F
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982803/
https://ncbi.nlm.nih.gov/pubmed/22395698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2694
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