טוען...
Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant
Definitive correction of disease causing mutations in somatic cells by homologous recombination (HR) is an attractive therapeutic approach for the treatment of genetic diseases. However, HR-based somatic gene therapy is limited by the low efficiency of gene targeting in mammalian cells and replicati...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982486/ https://ncbi.nlm.nih.gov/pubmed/24390279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.290 |
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