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Regulation of KLF4 turnover reveals an unexpected tissue specific role of pVHL in tumorigenesis
The transcription factor Krüppel-like factor 4 (KLF4) is an important regulator of cell fate decision, including cell cycle regulation, apoptosis, and stem cell renewal, and plays an ambivalent role in tumorigenesis as a tissue specific tumor suppressor or oncogene. Here we report that the Von Hippe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982234/ https://ncbi.nlm.nih.gov/pubmed/22284679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.031 |
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