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Optimization strategies for fast detection of positive selection on phylogenetic trees

Motivation: The detection of positive selection is widely used to study gene and genome evolution, but its application remains limited by the high computational cost of existing implementations. We present a series of computational optimizations for more efficient estimation of the likelihood functi...

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Bibliographische Detailangaben
Hauptverfasser: Valle, Mario, Schabauer, Hannes, Pacher, Christoph, Stockinger, Heinz, Stamatakis, Alexandros, Robinson-Rechavi, Marc, Salamin, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982156/
https://ncbi.nlm.nih.gov/pubmed/24389654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt760
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