Antibody against CD44s Inhibits Pancreatic Tumor Initiation and Post-Radiation Recurrence in Mice

BACKGROUND & AIMS: CD44s is a surface marker of tumor-initiating cells (TICs); high tumor levels correlate with metastasis and recurrence, as well as poor outcomes of patients. Monoclonal antibodies against CD44s might eliminate TICs with minimal toxicity. This strategy is unclear for treatment...

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Bibliographic Details
Main Authors:	Li, Ling, Hao, Xinbao, Qin, Jun, Tang, Wenhua, He, Fengtian, Smith, Amber, Zhang, Min, Simeone, Diane M., Qiao, Xiaotan T., Chen, Zhi-Nan, Lawrence, Theodore S., Xu, Liang
Format:	Artigo
Language:	Inglês
Published:	2014
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3982149/ https://ncbi.nlm.nih.gov/pubmed/24397969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.12.035
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Antibody against CD44s Inhibits Pancreatic Tumor Initiation and Post-Radiation Recurrence in Mice

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