Antibody against CD44s Inhibits Pancreatic Tumor Initiation and Post-Radiation Recurrence in Mice

BACKGROUND & AIMS: CD44s is a surface marker of tumor-initiating cells (TICs); high tumor levels correlate with metastasis and recurrence, as well as poor outcomes of patients. Monoclonal antibodies against CD44s might eliminate TICs with minimal toxicity. This strategy is unclear for treatment...

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Autori principali: Li, Ling, Hao, Xinbao, Qin, Jun, Tang, Wenhua, He, Fengtian, Smith, Amber, Zhang, Min, Simeone, Diane M., Qiao, Xiaotan T., Chen, Zhi-Nan, Lawrence, Theodore S., Xu, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982149/
https://ncbi.nlm.nih.gov/pubmed/24397969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.12.035
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