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Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using α(v)β(3)-Targeted Theranostic Nanoparticles
In nanomedicine, the hydrophobic nature of paclitaxel has favored its incorporation into many nanoparticle formulations for anti-cancer chemotherapy. At lower doses taxanes are reported to elicit anti-angiogenic responses. In the present study, the facile synthesis, development and characterization...
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Hoofdauteurs: | , , , , , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Ivyspring International Publisher
2014
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982128/ https://ncbi.nlm.nih.gov/pubmed/24723979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7581 |
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