Atherosclerotic Neovasculature MR Imaging with Mixed Manganese-Gadolinium Nanocolloids in Hyperlipidemic Rabbits

A high r1 relaxivity manganese-gadolinium nanocolloid (α(v)β(3)-MnOL-Gd NC) was developed and effectively detected atherosclerotic angiogenesis in rabbits fed cholesterol-rich diets for 12 months using a clinical MRI scanner (3T). 3D mapping of neovasculature signal intensity revealed the spatial co...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Wang, Kezheng, Pan, Dipanjan, Schmieder, Anne H., Senpan, Angana, Caruthers, Shelton D., Cui, Grace, Allen, John S., Zhang, Huiying, Shen, Baozhong, Lanza, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720435/
https://ncbi.nlm.nih.gov/pubmed/25652897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.12.008
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