Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using α(v)β(3)-Targeted Theranostic Nanoparticles

In nanomedicine, the hydrophobic nature of paclitaxel has favored its incorporation into many nanoparticle formulations for anti-cancer chemotherapy. At lower doses taxanes are reported to elicit anti-angiogenic responses. In the present study, the facile synthesis, development and characterization...

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Main Authors: Pan, Dipanjan, Schmieder, Anne H., Wang, Kezheng, Yang, Xiaoxia, Senpan, Angana, Cui, Grace, Killgore, Kendall, Kim, Benjamin, Allen, John S., Zhang, Huiying, Caruthers, Shelton D., Shen, Baozhong, Wickline, Samuel A., Lanza, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2014
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Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982128/
https://ncbi.nlm.nih.gov/pubmed/24723979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7581
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