Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using α(v)β(3)-Targeted Theranostic Nanoparticles

In nanomedicine, the hydrophobic nature of paclitaxel has favored its incorporation into many nanoparticle formulations for anti-cancer chemotherapy. At lower doses taxanes are reported to elicit anti-angiogenic responses. In the present study, the facile synthesis, development and characterization...

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Main Authors: Pan, Dipanjan, Schmieder, Anne H., Wang, Kezheng, Yang, Xiaoxia, Senpan, Angana, Cui, Grace, Killgore, Kendall, Kim, Benjamin, Allen, John S., Zhang, Huiying, Caruthers, Shelton D., Shen, Baozhong, Wickline, Samuel A., Lanza, Gregory M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ivyspring International Publisher 2014
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982128/
https://ncbi.nlm.nih.gov/pubmed/24723979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.7581
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