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PPAR agonist-mediated protection against HIV Tat-induced cerebrovascular toxicity is enhanced in MMP-9-deficient mice

The strategies to protect against the disrupted blood–brain barrier (BBB) in HIV-1 infection are not well developed. Therefore, we investigated the potential of peroxisome proliferator-activated receptor (PPAR) agonists to prevent enhanced BBB permeability induced by HIV-1-specific protein Tat. Expo...

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Hlavní autoři: Huang, Wen, Chen, Lei, Zhang, Bei, Park, Minseon, Toborek, Michal
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982084/
https://ncbi.nlm.nih.gov/pubmed/24424383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.240
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