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HIV-1 Tat-induced cerebrovascular toxicity is enhanced in mice with amyloid deposits

HIV-1-infected brains are characterized by elevated depositions of amyloid beta (Aβ); however, the interactions between Aβ and HIV-1 are poorly understood. In the present study, we administered specific HIV-1 protein Tat into the cerebral vasculature of 50–52 week old double transgenic (B6C3-Tg) mic...

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Bibliografske podrobnosti
Main Authors: Chen, Lei, Choi, Jeong June, Choi, Yean Jung, Hennig, Bernhard, Toborek, Michal
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206197/
https://ncbi.nlm.nih.gov/pubmed/21764480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.06.004
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