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Activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits human breast cancer cell line tumorigenicity
The effect of activation and over-expression of the nuclear receptor PPARβ/δ in human MDA-MB-231 (ER(−)) and MCF7 (ER(+)) breast cancer cell lines was examined. Target gene induction by ligand activation of PPARβ/δ was increased by over-expression of PPARβ/δ compared to controls. Over-expression of...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3981956/ https://ncbi.nlm.nih.gov/pubmed/24464939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0836 |
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