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Activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits human breast cancer cell line tumorigenicity

The effect of activation and over-expression of the nuclear receptor PPARβ/δ in human MDA-MB-231 (ER(−)) and MCF7 (ER(+)) breast cancer cell lines was examined. Target gene induction by ligand activation of PPARβ/δ was increased by over-expression of PPARβ/δ compared to controls. Over-expression of...

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Hlavní autoři: Yao, Pei-Li, Morales, Jose L., Zhu, Bokai, Kang, Boo-Hyon, Gonzalez, Frank J., Peters, Jeffrey M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981956/
https://ncbi.nlm.nih.gov/pubmed/24464939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0836
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