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Blockade of hypocretin receptor-1 preferentially prevents cocaine seeking: comparison with natural reward seeking

Hypothalamic orexin/hypocretin (Orx/Hcrt) peptides participate in the regulation of a wide range of physiological processes and are recruited by drugs of abuse. To advance our understanding of the potential of the Orx/Hcrt receptor-1 (Hcrt-r1) as a treatment target for cocaine addiction, the effect...

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Détails bibliographiques
Auteurs principaux: Martin-Fardon, Rémi, Weiss, Friedbert
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981907/
https://ncbi.nlm.nih.gov/pubmed/24407199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000120
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