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N-(2-Methyl-6-benzoxazolyl)-N′-1,5-n aphthyridin-4-yl urea (SB334867), a hypocretin receptor-1 antagonist, preferentially prevents ethanol seeking: comparison with natural reward seeking

Orexins/hypocretins (Orx/Hcrt) are hypothalamic peptides that regulate a wide range of physiological processes and have been shown to be recruited by drugs of abuse. This study was designed to test the effect of the specific Orx/Hcrt receptor-1 (Hcrt-r1) antagonist SB334867 on reinstatement elicited...

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Detalles Bibliográficos
Autores principales: Martin-Fardon, R., Weiss, F
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491173/
https://ncbi.nlm.nih.gov/pubmed/22830647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00480.x
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