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Multi-therapeutic potential of autoantibodies induced by immune complexes trapped on follicular dendritic cells

Induction of autoantibodies (autoAbs) targeting disease drivers / mediators is emerging as a potential immunotherapeutic strategy. Auto-immune complex (IC)-retaining follicular dendritic cells (FDCs) critically regulate pathogenic autoAb production in autoreactive germinal centers (GCs); however, th...

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Detalhes bibliográficos
Main Authors: El Shikh, Mohey Eldin, Kmieciak, Maciej, Manjili, Masoud H, Szakal, Andras K, Pitzalis, Costantino, Tew, John G
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981854/
https://ncbi.nlm.nih.gov/pubmed/23836278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.25596
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